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	<title>Bioinformatics Hub | H. Shin | Activity</title>
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				<title>H. Shin replied to the topic What is Proteolysis-Targeting Chimera? in the forum Discussion</title>
				<link>https://bioinformaticshub.net/forums/topic/what-is-proteolysis-targeting-chimera/#post-2304</link>
				<pubDate>Sun, 18 Dec 2022 09:56:53 +0000</pubDate>

									<content:encoded><![CDATA[<p>A proteolysis targeting chimera (PROTAC) is a heterobifunctional small molecule composed of two active domains and a linker, capable of removing specific unwanted proteins. Rather than acting as a conventional enzyme inhibitor, a PROTAC works by inducing selective intracellular proteolysis.</p>
<p>PROTACs consist of two covalently linked&hellip;<span class="activity-read-more" id="activity-read-more-978"><a href="https://bioinformaticshub.net/forums/topic/what-is-proteolysis-targeting-chimera/#post-2304"target="_blank" rel="nofollow ugc">Read more</a></span></p>
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