Exosomes are membranous nanovesicles of endocytic origin released by most cell types from diverse organisms. Exosomes are present in many and perhaps all biological fluids, including blood, urine, and cultured medium of cell cultures. Exosomes play a critical role in cell-cell communication. There is a growing interest in the clinical applications of exosomes. Exosomes can potentially be used for prognosis, therapy, and biomarkers for health and disease. As exosomes contain RNA, proteins and lipids, there is a significant interest in characterizing the molecular cargo of exosomes. The following are some exosome databases that may be helpful for different researchers:
ExoCarta is a free web-based community resource. It is a manually curated database of exosomal proteins, RNA, and lipids. The database catalogs information from both published and unpublished exosomal studies.
miREV was developed as an easy-to-use online tool with a graphical user interface. Main goal is to uncover potential reference RNAs from EV studies in relation to different experimental conditions.
deepBase v3.0 added ncRNAs expression profiles of exosomes.
Vesiclepedia is a web-based compendium of RNA, proteins, lipids, and metabolites that are identified in extracellular vesicles from both published and unpublished studies.
EVmiRNA is a database of miRNA profiling in extracellular vesicles.
exoRBase is a repository of extracellular vesicles (EVs) long RNAs (exLRs) derived from RNA-seq data analyses in different human body fluids. The exLRs contain messenger RNA (mRNA), long non-coding RNA (lncRNA), and circular RNA (circRNA).
miRandola is a curated knowledge base of non-invasive biomarkers, with an effort to update and collect the accumulating information on extracellular ncRNAs that is spread across scientific publications and different databases.
Urinary Exosome Protein Database is based on published protein mass spectrometry data from the NHLBI (national Heart, Lung, and Blood Institute) Epithelial Systems Biology Laboratory (ESBL). All data are from urinary exosomes isolated from healthy human volunteers.
EV-TRACK platform captures technical and biological features of extracellular vesicles (EV) and EV-related isolation and characterization recipes and informs researchers about (in)complete reporting of these recipes.
ExoBCD is a comprehensive database for exosomal biomarker discovery in breast cancer.
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