Do all RNA start out as primary transcripts?

[Anya Solo]

Do all RNA start out as primary transcripts before they can be translated into proteins?

[Yan Zou]

Yes, all RNAs are synthesized first as primary transcript. This transcript is processed to produce mature RNA, whether mRNA, rRNA, tRNA, or any other RNA.

[J. Kirkband]

When an RNA transcript is first made in a eukaryotic cell, it is considered a pre-mRNA and must be processed into a messenger RNA (mRNA). A 5’ cap is added to the beginning of the RNA transcript, and a 3’ poly-A tail is added to the end. In splicing, some sections of the RNA transcript (introns) are removed, and the remaining sections (exons) are stuck back together.

So yes, all RNAs start out as primary transcripts before they can be translated into proteins.

[D. Jenko]

All forms of RNA are made on a DNA template. The synthesis of RNA is performed by enzymes called RNA polymerases.

This process is called transcription. The first step in decoding genetic messages is transcription, during which a nucleotide sequence is copied from DNA to RNA. In transcription, a DNA sequence is rewritten, or transcribed, into a similar RNA “alphabet”.

The primary transcript should then undergo processing to produce different RNA types. Some transcripts can undergo alternative splicing, making different mRNAs and proteins from the same RNA transcript.

 

[D. Yousof]

Here you can find all you need to know about RNA:

RNA – Wikipedia

 

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