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  • in reply to: What is sea nomads’ gene? #3840
    Robin
    Participant

      How can variant of the PDE10A gene cause larger spleens?

      What about how the other mentioned genes function?

      I mean molecular mechanisms.

      in reply to: What is sea nomads’ gene? #3831
      Robin
      Participant

        What about the gene/genes?

        Robin
        Participant

          Gene knockout and gene knockdown are two mechanisms of silencing the expression of genes inside organisms. Gene knockout is applicable at DNA level while gene knockdown is applicable at RNA level.

          Gene knockout involves the complete erasing of target genes or inactivating them through nonsense mutations whereas gene knockdown is through abortion of protein translation and degradation of the mRNA.

           

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