SMA Base Editing Can Work
Written by Fazil Hussein: SMA base editing, or base editing implementation for treatment of spinal muscular atrophy, was successful in cell and mouse models according to a recent article. Spinal muscular…
Latest news about research and practice of biotechnology.
Written by Fazil Hussein: SMA base editing, or base editing implementation for treatment of spinal muscular atrophy, was successful in cell and mouse models according to a recent article. Spinal muscular…
Written by A. Hammouda: “CRISPR embryo errors can be underestimated” is a conclusion drawn by the research published in Nature Communications a few days ago. There are still trials to push…
Researchers at the University of Cambridge, UK reported a general approach, Chem-map, to establish drug-chromatin binding maps. These are in situ interaction maps for small molecules that bind to cellular…
Written by A. Hammouda: Make People Better is the title of the documentary released in 2022, which revolves around the Chinese scientist He Jiankui and his CRISPR human genome editing,…
A recent publication in the Journal of the American Chemical Society describes a new trial using a cancer-targeting artificial DNA to target cancer cells for destruction by the immune system.…
Written by A. Hammouda: A recent article in Nature Neuroscience asserted the success of RNA-targeting CRISPR-Cas13d system in alleviating disease-related phenotypes in Huntington’s disease models. Huntington’s disease Huntington’s disease (HD)…
A team from MIT describes this new tool, PASTE DNA editing that delivers genes as long as 36,000 DNA base pairs to several types of cells. The research is published…
The Nobel Committee awarded the 2022 Nobel Prize for old DNA research. On the third of October 2022, The Nobel Assembly at Karolinska Institutet decided to award the 2022 Nobel Prize…
Scientists led by researchers from the Transmission:Zero team at Imperial College London have engineered genetically modified mosquitoes that slow the growth of malaria-causing parasites in their guts, and prevent transmission…
There has been a discussion here about liquid biopsy and cancer blood test that detects multiple cancers. A recent article in Medscape Medical News gives an update on the Galleri…
Unrelated twins are no longer a myth. New findings published in Cell Reports suggest that apparent facial similarity between unrelated people extend to DNA and other similarities. The human face…
Aneuploidy detection by Nanopore DNA sequencing is a newly developed prenatal test. It can determine if a fetus or embryo has the right number of chromosomes at a fraction of…
Respiratory diseases are a global burden, with millions of deaths attributed to pulmonary illnesses and dysfunctions. Therapeutics and vaccines have been developed, but they present major limitations regarding pulmonary bioavailability…
Zolgensma, as posted earlier here, is the promising life-saving one-time gene therapy for patients with spinal muscular atrophy (SMA). Shocking news about patient death after Zolgensma was published this week.…
A bioengineered corneal tissue has been developed using collagen protein from pig’s skin. Porcine dermal collagen was chemically and photochemically bioengineered into an implantable tissue mimicking the human corneal extracellular…