Bioinformatics Hub | Site-Wide Activity https://bioinformaticshub.net/activity/ Activity feed for the entire site. Tue, 03 Nov 2026 05:37:23 +0000 https://buddypress.org/?v= en-US 30 hourly 2 3e9adb68a9b4146a6c664c7e0fd2c7cf Conoceme... became a registered member https://bioinformaticshub.net/activity/p/3785/ Tue, 03 Nov 2026 05:37:19 +0000 0 b4ae498cde2015e7746cc7d8f4767bf8 Me gusta el brulн became a registered member https://bioinformaticshub.net/activity/p/3783/ Tue, 03 Nov 2026 03:26:51 +0000 0 e73fb7519f8cfea45a4c23e702b55186 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4896 Mon, 02 Nov 2026 13:46:08 +0000 AI Protein Design: Creating Tomorrow’s Therapeutic Proteins Artificial intelligence (AI) protein design is rapidly transforming biotechnology. Instead of spending years searching for naturally occurring […]

]]> 0 fb87452f9f1d008e2db072422337f26c A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4884 Fri, 30 Oct 2026 16:02:00 +0000 Cancer Vaccines: Fact, Fiction, and the Future of Personalized Cancer Immunotherapy Cancer vaccines have long captured the public imagination, promising a future where the immune system can be trained to prevent or even eliminate […]

]]> 0 f34230774481b33b2b7096357c43fc72 Dr. Kumar replied to the topic Is cancer vaccine a fact? in the forum Discussion https://bioinformaticshub.net/forums/topic/is-cancer-vaccine-a-fact/#post-4883 Thu, 29 Oct 2026 06:29:46 +0000 Yes.

Read this post

Cancer Vaccines: Preventive & Therapeutic Types – HCG

 

]]> 0 2defe468ec001fab866e24256b03737f Dr. M replied to the topic Is cancer vaccine a fact? in the forum Discussion https://bioinformaticshub.net/forums/topic/is-cancer-vaccine-a-fact/#post-4882 Thu, 29 Oct 2026 06:18:29 +0000 Yes. Cancer vaccines are real, and some are already approved for use. They fall into two main categories:

1. Preventive Cancer Vaccines

These vaccines help prevent cancers caused by certain viruses.

Examples:

HPV vaccine (Gardasil 9) helps prevent cervical cancer, anal cancer, penile cancer, vulvar cancer, vaginal cancer, and some head and…Read more

]]> 0 1f20389040ef5f9b7f5ffef53f7ef87f Alice K started the topic Is cancer vaccine a fact? in the forum Discussion https://bioinformaticshub.net/forums/topic/is-cancer-vaccine-a-fact/ Tue, 27 Oct 2026 18:21:25 +0000 Is cancer vaccine a fact? How does it work? and for what cancer?

]]> 0 49a38948b98661abc2b8d0723e04c2e0 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4870 Mon, 26 Oct 2026 08:14:08 +0000 Large Language Models Are Reshaping Biological Research Large Language Models (LLMs) are rapidly becoming valuable tools in biological research. While many people associate LLMs with chatbots and content […]

]]> 0 5689fc9806d7a055cd77a2161b2e35f1 Dr. Asim replied to the topic How many alleles are there for ABO blood groups? in the forum Discussion https://bioinformaticshub.net/forums/topic/how-many-alleles-are-there-for-abo-blood-groups/#post-4868 Sun, 25 Oct 2026 10:50:47 +0000 The ABO gene encodes a glycosyltransferase enzyme that modifies the H antigen on the surface of red blood cells.

Depending on the allele:

IA adds N-acetylgalactosamine → A antigen.

IB adds galactose → B antigen.

i produces a nonfunctional enzyme → no modification, leaving the H antigen unaltered (blood group O).

]]> 0 8659c62258fad5ad850aca5e078e1a74 Lisa C started the topic How many alleles are there for ABO blood groups? in the forum Discussion https://bioinformaticshub.net/forums/topic/how-many-alleles-are-there-for-abo-blood-groups/ Sat, 24 Oct 2026 18:10:31 +0000 How many alleles are there for ABO blood groups? Two or three?

I am seriously confused.

]]> 0 fc77501b671de33b6792245dee14054f Dr. M posted an update: New Push to Make Editing Human Embryos Legal Comes Under […] https://bioinformaticshub.net/activity/p/3769/ Fri, 23 Oct 2026 17:43:16 +0000 New Push to Make Editing Human Embryos Legal Comes Under Scrutiny
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https://www.the-scientist.com/new-push-to-make-editing-human-embryos-legal-comes-under-scrutiny-75125?

]]> 0 880200b5f1995a72971151fddc3e6e9e A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4853 Thu, 22 Oct 2026 12:27:10 +0000 AI-Powered Protein Folding: Beyond AlphaFold AI-Powered Protein Folding has transformed bioinformatics, reshaping how scientists understand protein structures and accelerating breakthroughs in […]

]]> 0 07e584c20790022cdc8822ac6fab978b A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4840 Mon, 19 Oct 2026 14:21:22 +0000 Leber Congenital Amaurosis: Gene Therapy Breakthroughs Leber Congenital Amaurosis is at the forefront of gene therapy research, with recent advances offering hope to children born blind. Cutting‑edge t […]

]]> 0 8debb7c990ad2c77bf3e3972e5642152 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4829 Sat, 17 Oct 2026 06:37:13 +0000 Gene Therapy for Congenital Blindness: Latest Breakthroughs in 2026 Gene therapy for congenital blindness has become one of the most exciting frontiers in ophthalmology. In 2026, new clinical trials and experimental […]

]]> 0 2ed579ac1840e3af7b93d4f99cc6a2f8 Y Soun posted an update: Whitepaper Gene Editing Precision Depends on Guide RNA […] https://bioinformaticshub.net/activity/p/3747/ Fri, 16 Oct 2026 08:29:46 +0000 Whitepaper
Gene Editing Precision Depends on Guide RNA Quality
Reduce synthesis-related impurities and support target recognition with gRNA purification
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https://www.the-scientist.com/gene-editing-precision-depends-on-guide-rna-quality-75105?

]]> 0 761c93803a93c34f9c6e125080827693 Fazil Hussein replied to the topic What is it about a new gene therapy that restored vision to a boy born blind? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-it-about-a-new-gene-therapy-that-restored-vision-to-a-boy-born-blind-3/#post-4824 Fri, 16 Oct 2026 08:22:19 +0000 The congenital eye disease treated was Leber Congenital Amaurosis type 4 (LCA4), caused by mutations in the AIPL1 gene. The normal product of this gene is the aryl hydrocarbon receptor-interacting protein-like 1, which is essential for stabilizing and folding photoreceptor proteins (especially PDE6) in retinal cells.

The treatment was performed…Read more

]]> 0 c85a4ad118b2e4ade9ed45999d305aaf Marzana M started the topic What is it about a new gene therapy that restored vision to a boy born blind? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-it-about-a-new-gene-therapy-that-restored-vision-to-a-boy-born-blind-3/ Wed, 14 Oct 2026 14:53:43 +0000 I read in the news that a new gene therapy restored vision to a boy born blind. Can anyone explain this?

]]> 0 6d7ff3c07e86e126fdf16e79f1790278 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4799 Tue, 13 Oct 2026 08:17:21 +0000 Unlocking Precision Medicine: How AI-Powered Genomic Variant Calling with DeepVariant is Changing Bioinformatics Understanding the human genome requires identifying the unique differences in our DNA. For years, bioinformaticians have relied on complex […]

]]> 0 c5b69114607cfc6df6c6f6b2aeb7c553 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4786 Sun, 11 Oct 2026 08:52:03 +0000 Optogenetics Breakthrough Restores Sight The Optogenetics Breakthrough marks a turning point in neuroscience and ophthalmology. By harnessing light‑sensitive proteins to reprogram retinal c […]

]]> 1 35f05541c1ebc4befacdc0f89c95fba4 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4778 Fri, 09 Oct 2026 14:19:54 +0000 Optogenetics Nobel Prize 2026 – Breakthrough in Neuroscience Optogenetics Nobel Prize Shines on Neuroscience. The 2026 Nobel Prize in Physiology or Medicine was awarded to Karl Deisseroth, Peter Hegemann, and […]

]]> 1 135bad41f4c5107966ecfb4d99a54103 Fazil Hussein replied to the topic What is optogenetics? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-optogenetics/#post-4776 Fri, 09 Oct 2026 08:28:02 +0000 The 2026 Nobel Prize in Physiology or Medicine was awarded jointly to Karl Deisseroth, Peter Hegemann, and Georg Nagel for their groundbreaking discoveries on light-gated ion channels and the development of optogenetics, a technique that allows scientists to control nerve cell activity with light.

]]> 0 87bf0f43bb3b16c6cd0a42a5312aa495 A. Hammouda replied to the topic What is optogenetics? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-optogenetics/#post-4774 Thu, 08 Oct 2026 08:28:54 +0000 Optogenetics doesn’t have anything to do with inheriting eye diseases. It might sound misleading at first if you assume “opto” refers to eyes or vision, but in scientific language “opto” just means light. The confusion comes from everyday usage where “optical” is often linked to eyesight.

Optogenetics is actually a cutting‑edge neuroscience tec…Read more

]]> 0 3b0c00e7bba4e3ede46ea205295c8ebd Dr. M posted an update: Webinar Considerations for Selecting Molecular Methods for […] https://bioinformaticshub.net/activity/p/3725/ Wed, 07 Oct 2026 11:59:18 +0000 Webinar
Considerations for Selecting Molecular Methods for Biomarker Assessment in Hematologic Malignancies
Explore how next-generation sequencing, digital PCR, and emerging whole-genome sequencing approaches can support sensitive measurable residual disease detection and biomarker assessment in acute myeloid…Read more

]]> 0 43272a5fc7b6b8f60cc4dacc75e88c00 Mahi Bashat started the topic What is optogenetics? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-optogenetics/ Wed, 07 Oct 2026 06:53:51 +0000 What is meant by optogenetics?
Does it describe inheritance of eye diseases or what?

]]> 0 158cc8859c09157f375edf26af45e999 Fiwfan.app became a registered member https://bioinformaticshub.net/activity/p/3720/ Tue, 06 Oct 2026 11:35:10 +0000 0 e4fb38f62e28d08c230c882f0d2bf44e Hamdy Ahmad posted an update: Interesting. https://www.pnas.org/post/journal-club/chromos […] https://bioinformaticshub.net/activity/p/3719/ Mon, 05 Oct 2026 17:59:54 +0000 Interesting.

https://www.pnas.org/post/journal-club/chromosomes-aren-t-carefully-folded-dna-they-re-dual-phase-gels

]]> 0 49b705c2affb66934a13e6dee0a275f1 A. Hammouda wrote a new post https://bioinformaticshub.net/?p=4753 Sun, 04 Oct 2026 15:24:16 +0000 AI Tools Transforming Bioinformatics Research AI tools are transforming the bioinformatics research. Artificial intelligence is no longer just a buzzword—it’s becoming a cornerstone of mod […]

]]> 0 776cb5bc8fa78973a2e729f0e9417536 BioHub posted an update: Apologies are due to all for the technical error that caused […] https://bioinformaticshub.net/activity/p/3715/ Sat, 03 Oct 2026 13:52:23 +0000 Apologies are due to all for the technical error that caused the site to be down lately.

]]> 0 9d7c07aa5bb15ef793a2a63325fe3db0 A. Hammouda posted an update: Webinar Best Practices for qPCR Assay Design and […] https://bioinformaticshub.net/activity/p/3712/ Thu, 01 Oct 2026 14:39:17 +0000 Webinar
Best Practices for qPCR Assay Design and Optimization
Explore practical strategies for designing, optimizing, and validating qPCR assays to improve specificity, reproducibility, and confidence across routine and high-throughput gene expression studies.
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https://www.the-scientist.com/best-practices-for-qpcr-assay-design-and-optimization-74948?

]]> 0 930f9b92dcd1833048372f8b4dc93144 Dr. M posted an update: Webinar Essential Genes Are Dominantly Activated by Single […] https://bioinformaticshub.net/activity/p/3705/ Mon, 28 Sep 2026 18:10:18 +0000 Webinar
Essential Genes Are Dominantly Activated by Single Transcription Factors
Discover how single-molecule Fiber-seq is revealing unexpected mechanisms of transcription factor regulation, chromatin accessibility, and essential gene activation at CpG-island promoters.
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See link in my last post

]]> 0 416006c939628744e2f0b41f30e9ffce A. Hammouda posted an update: Webinar Considerations for Selecting Molecular Methods for […] https://bioinformaticshub.net/activity/p/3699/ Fri, 25 Sep 2026 14:05:50 +0000 Webinar
Considerations for Selecting Molecular Methods for Biomarker Assessment in Hematologic Malignancies
Explore how next-generation sequencing, digital PCR, and emerging whole-genome sequencing approaches can support sensitive measurable residual disease detection and biomarker assessment in acute myeloid…Read more

]]> 0 b0673dd6df5f8acbc0c64d44478214e8 Dr. M posted an update: Webinar Essential Genes Are Dominantly Activated by Single […] https://bioinformaticshub.net/activity/p/3694/ Tue, 22 Sep 2026 11:21:32 +0000 Webinar
Essential Genes Are Dominantly Activated by Single Transcription Factors
Discover how single-molecule Fiber-seq is revealing unexpected mechanisms of transcription factor regulation, chromatin accessibility, and essential gene activation at CpG-island…Read more

]]> 0 01f01684c736f4fd71fbacf1d4de50b7 A. Hammouda posted an update: Webinar Best Practices for qPCR Assay Design and […] https://bioinformaticshub.net/activity/p/3691/ Sat, 19 Sep 2026 11:10:08 +0000 Webinar
Best Practices for qPCR Assay Design and Optimization
Explore practical strategies for designing, optimizing, and validating qPCR assays to improve specificity, reproducibility, and confidence across routine and high-throughput gene expression studies.
.
https://www.the-scientist.com/best-practices-for-qpcr-assay-design-and-optimization-74948?

]]> 0 1fb499f9461c894203406c51404db2e5 Hamdy Ahmad replied to the topic Can any one state briefly differences between CHIP, CUT&RUN, CUT&TAG Sequencing? in the forum Discussion https://bioinformaticshub.net/forums/topic/can-any-one-state-briefly-differences-between-chip-cutrun-cuttag-sequencing/#post-4727 Fri, 04 Sep 2026 12:32:31 +0000 ChIP-seq (Chromatin Immunoprecipitation Sequencing)

Cells are crosslinked to preserve protein–DNA interactions.

Chromatin is fragmented (usually by sonication).

Antibodies pull down the protein of interest along with bound DNA.

The DNA fragments are purified and sequenced to identify binding sites.

 

CUT&RUN (Cleavage Under Targets & R…Read more

]]> 0 db2fe22cd4f75ae47225564f545ca727 Dr. M replied to the topic Can any one state briefly differences between CHIP, CUT&RUN, CUT&TAG Sequencing? in the forum Discussion https://bioinformaticshub.net/forums/topic/can-any-one-state-briefly-differences-between-chip-cutrun-cuttag-sequencing/#post-4723 Thu, 03 Sep 2026 09:33:36 +0000 ChIP-seq, CUT&RUN, and CUT&Tag are all methods to study protein–DNA interactions and histone modifications, but they differ mainly in input requirements, resolution, background noise, and workflow efficiency. In short: ChIP-seq is the traditional gold standard but requires large samples and has high background; CUT&RUN improves precision with l…Read more

]]> 0 5dcbf8e5393ef8be74510a8b51627a65 A. Hammouda started the topic Can any one state briefly differences between CHIP, CUT&RUN, CUT&TAG Sequencing? in the forum Discussion https://bioinformaticshub.net/forums/topic/can-any-one-state-briefly-differences-between-chip-cutrun-cuttag-sequencing/ Wed, 02 Sep 2026 09:03:39 +0000 Can anyone state briefly differences between CHIP, CUT&RUN, CUT&TAG Sequencing?

]]> 0 866a8be744bed01949d98e2613881f68 W. Norman posted an update: Bringing Large-Scale Genomics to Labs of Every Size A […] https://bioinformaticshub.net/activity/p/3638/ Wed, 26 Aug 2026 07:48:58 +0000 Bringing Large-Scale Genomics to Labs of Every Size
A compact sequencing device with integrated analysis capabilities enables researchers to tackle comprehensive genomics without the traditional infrastructure burden.
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https://www.the-scientist.com/bringing-large-scale-genomics-to-labs-of-every-size-74876?

]]> 0 35ebc1913f8e551242f9d4d53f0b53f4 A. Hammouda posted an update: Gene Switch Uses Electromagnetic Fields to Control Genes […] https://bioinformaticshub.net/activity/p/3630/ Thu, 20 Aug 2026 16:23:31 +0000 Gene Switch Uses Electromagnetic Fields to Control Genes Remotely.
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Gene Switch Uses Electromagnetic Fields to Control Genes Remotely

]]> 0 6351ac790266db20675950e2025c42d7 Dr. M replied to the topic What is the role of CRISPR and the guide RNA in gene editing? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-the-role-of-crispr-and-the-guide-rna-in-gene-editing/#post-4705 Mon, 10 Aug 2026 07:18:13 +0000 This question highlights an important naming distinction. It helps to separate what the name actually stands for in nature from how scientists use the term today.

In Nature:

CRISPR stands for “Clustered Regularly Interspaced Short Palindromic Repeats”. It is actually a region in a bacterium’s own DNA genome that acts as an immune memory library.…Read more

]]> 0 dae3706c1dec84d9c67ad477437884b4 A. Hammouda replied to the topic What is the role of CRISPR and the guide RNA in gene editing? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-the-role-of-crispr-and-the-guide-rna-in-gene-editing/#post-4704 Sun, 09 Aug 2026 06:15:13 +0000 CRISPR stands for:

Clustered Regularly Interspaced Short Palindromic Repeats

Clustered – They are grouped together in clusters on the bacterial DNA.

Regularly Interspaced – The repeating sequences are evenly spaced apart by “spacer” sequences (which are the viral DNA fragments the bacterium has collected).

Short – Each repeat is only about…Read more

]]> 0 415a13180a47437a3be5eca27058b83b A. Hammouda posted an update: eBook Translating Cancer Biomarker Research Integrating […] https://bioinformaticshub.net/activity/p/3619/ Sun, 09 Aug 2026 05:49:43 +0000 eBook
Translating Cancer Biomarker Research
Integrating broad scope high-throughput omics technologies with targeted analytical validation assays enables translational cancer biomarker research workflows.
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https://www.the-scientist.com/translating-cancer-biomarker-research-74569?

]]> 0 bd67844148ff3f5760571415c08f4d19 Fazil Hussein replied to the topic What is the role of CRISPR and the guide RNA in gene editing? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-the-role-of-crispr-and-the-guide-rna-in-gene-editing/#post-4703 Fri, 07 Aug 2026 16:12:52 +0000 CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. These are DNA sequences found naturally in bacteria and archaea.

They function as a kind of genetic memory: bacteria store snippets of viral DNA inside CRISPR arrays after surviving infections.

When the same virus attacks again, the cell transcribes these stored…Read more

]]> 0 42a9366802669bc483de41700b427bb8 A. Hammouda posted an update: Two decades after the human genome project, researchers from […] https://bioinformaticshub.net/activity/p/3617/ Thu, 06 Aug 2026 16:36:00 +0000 Two decades after the human genome project, researchers from the Telomere-to-Telomere (T2T) Consortium have reconstructed the complete human genome.
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T2T Consortium Completes Full Diploid Human Genome Reconstruction

]]> 0 80d7fd7d9f891f4efd6cc3b0e19f35bf Modern Incense Holder became a registered member https://bioinformaticshub.net/activity/p/3614/ Thu, 06 Aug 2026 09:53:01 +0000 0 4c365e2e2151c28fb4b287b4574b8f7b Mahi Bashat started the topic What is the role of CRISPR and the guide RNA in gene editing? in the forum Discussion https://bioinformaticshub.net/forums/topic/what-is-the-role-of-crispr-and-the-guide-rna-in-gene-editing/ Wed, 05 Aug 2026 20:34:39 +0000 What is the role of CRISPR and the guide RNA in gene editing?

If guide RNA recognizes the cut site and Cas9 cuts DNA, then what is the role of CRISPR?

]]> 0 5d631b871e83778f1fa5534985e2c7ef A. Hammouda posted an update: eBook Showcasing the Importance of Molecular Testing for […] https://bioinformaticshub.net/activity/p/3608/ Thu, 30 Jul 2026 08:23:00 +0000 eBook
Showcasing the Importance of Molecular Testing for Vector-Borne Diseases.
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https://www.the-scientist.com/showcasing-the-importance-of-molecular-testing-for-vector-borne-diseases-73298?

]]> 0 29ddd81571e760d268b501b3d0708aac A. Hammouda posted an update https://bioinformaticshub.net/activity/p/3607/ Wed, 29 Jul 2026 08:29:47 +0000
Girl, 11, becomes first UK patient to have ‘groundbreaking’ gene therapy to save her sight.
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https://www.independent.co.uk/news/health/gene-therapy-bardet-biedl-syndrome-meiragtx-b3021021.html?
]]> 0 db1c7feebbe832d5d83d1a65eb54ae41 Kevinpoopy became a registered member https://bioinformaticshub.net/activity/p/3605/ Sat, 25 Jul 2026 20:56:42 +0000 0 611dc2393853c2786793a2868d3b49b9 Richardgit became a registered member https://bioinformaticshub.net/activity/p/3603/ Thu, 23 Jul 2026 19:13:06 +0000 0 25af0e6c247dcf770fb6a798ca37d561 Jameskar became a registered member https://bioinformaticshub.net/activity/p/3599/ Tue, 21 Jul 2026 02:04:16 +0000 0